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Fetal blood levels technique maternal blood levels subsequent parenteral administration. Withdrawal signs manifest in infants born to Gals who get barbiturates all through the previous trimester of pregnancy (see DRUG ABUSE AND DEPENDENCE). If phenobarbital is employed for the duration of pregnancy or When the affected individual gets to be pregnan

Nonteratogenic Effects. Studies of infants struggling from long-phrase barbiturate publicity in utero involved the acute withdrawal syndrome of seizures and hyperirritability from beginning to your delayed onset of as many as 14 days (see DRUG ABUSE AND DEPENDENCE).Alkalinization of urine hastens phenobarbital excretion, but dialysis and hemoperfus